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It is therefore suggesting that the slight change of relaxation observed in the aorta without endothelium ex vivo might be due to some mechanism unrelated to the direct nitric oxide stimulation which needs further investigation

Thyroid tumors : GLP-1s carry warnings about the potential risk of developing thyroid tumors

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Because of this potential risk, the medication is contraindicated (should not be used) in people with a personal or family history of MTC or in those with an endocrine condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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